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New research on erectile
dysfunction
The flaccid state of organ is showing new pathway to treat
ED
Researchers at the Medical College of Georgia are working
on a new approach to treat Erectile
Dysfunction. Instead of relaxing the penile muscles
with the existing line of treatment like Viagra the
new research is exploring the pathway which involves
reducing the contraction of smooth muscles.
An experimental drugY-27632 has been used in an animal
model to check Rho- kinase, an enzyme central to smooth
muscle contraction; the result was an immediate, sustainable
erection could be achieved thereby.
Dr. Thomas M. Mills, MCG physiologist and investigator
on the study said,"it's a dramatic response which
leaves us hopeful that we have found a potential new
approach to treating erectile dysfunction,"
Erectile dysfunction is to do with Men’s
Sexual Health problem wherein an affected man is
either unable to or able to briefly sustain erection
of his organ at the time of Sexual
Intercourse.
"We are very excited about this research because
it takes a unique approach that has not been looked
at before,"said Dr. Ronald W. Lewis, chief of the
MCG Section of Urology and consultant on the Y-27632
study. The new ED research focuses on the fact that
most of the time penis remains in flaccid state. Thus
working on the line of what causes smooth relaxation
was logical.
Unlike in case of rest of the body, it is the muscular
relaxation which is working to bring an organ to its
functional state. This means, as the researchers explain,
there is a constant release of vasoconstrictors in the
blood stream which keep the smooth muscles of the organ
contracted, thus keeping it flaccid.
The continuing research on ED stems from the fact
that the existing line of medication is unable to treat
the problem in all men. This indicates that ED may not
be happening as a result of the disturbance in one pathway
only. Hence the search for new pathways and the drugs
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