On
21st November, 2003 , The Food and Drug Administration
(FDA) approved Cialis (Tadalafil), an oral medication
to treat
erectile dysfunction
(ED, or impotence) in men. This is the third oral product
approved for this condition.
Cialis is different than currently approved
products for ED like Viagra and Levitra because it
stays in the body longer.
Manufacturer :
Cialis is manufactured by Lilly ICOS LLC ( Eli Lilly and ICOS ) .
Mode of Action :
Cialis acts by relaxing muscles in the penis and blood vessels, allowing increased blood flow into the penis, which produces an erection.
Clinical Trials :
Nearly 4,000 men with erectile dysfunction under went
random, placebo-controlled trials clinical trials.
In two of these trials, men had ED associated with
diabetes mellitus
or following radical prostatectomy for prostate cancer.
The drug's effectiveness was assessed using a sexual function questionnaire. In addition, patients were asked to report if they were able to achieve an erection adequate for intercourse and whether that erection was maintained to allow completion of intercourse.
In all of these trials, Cialis improved patients' ability to achieve and maintain a penile erection. In other studies, sexual activity was improved in some patients at 30 minutes after taking a dose; additional studies demonstrated improvements for up to 36 hours after taking Cialis when compared to placebo.
Recommended Dose:
- Cialis should not be used more than once per day.
- The recommended starting dose for most patients is 10 mg taken prior to anticipated sexual activity.
- A higher dose of 20mg is prescribed for patients whose response to the 10mg dose is not adequate.
- A lower dose (5 mg) recommended for patients taking other medicines or having medical conditions that may decrease the body's ability to metabolize Tadalafil.
Cialis does not protect from AIDS or other sexually transmitted diseases.
Source : http://www.fda.gov/
