Cialis Is Effective In The Treatment Of Men With Erectile Dysfunction Regardless Of Previous Effective Viagra Use
April 25, 2006

The phosphodiesterase type 5 (PDE-5) inhibitors have revolutionized the pharmacologic management of erectile dysfunction (ED). Viagra (sildenafil citrate) was the first of the class to be introduced in 1998 and later followed by Levitra (Vardenafil) and Cialis (Tadalafil) in 2003. Therefore, men currently taking Cialis may have had previous experience with Viagra. Because of the unique properties of each drug, many patients will try more than one of these agents.

Dr. Broderick of the Mayo clinic in Jacksonville, Florida and colleagues recently reviewed 14 placebo controlled, double-blinded trials of Cialis use in men who were either previous Viagra responders or naïve to the PDE-5 class of medications. A total of almost 2800 men were analyzed for this study. Patients who failed to have an erectile response to Viagra were excluded from this analysis.

The investigators found that Cialis at 10 or 20 mg improved erectile function over placebo regardless of previous Viagra use or PDE-5 inhibitor naive patients. Conclusions were based on results measured by the International Index of Erectile Function (IIEF) EF domain score, Sexual Encounter Profile (SEP) questions Q2 (successful penetration) and Q3 (successful intercourse) and a Global Assessment Question (GAQ1) about erectile improvement.

Source: http://www.medicalnewstoday.com/medicalnews.php?newsid=42135&nfid=rssfeeds