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The high cost of being Lilly
January 31, 2004

Cymbalta, Zyprexa, Humulin, Humalog, Stattera, Cialis, Forteo, and Gemzar. It sounds like an orchestra of newly invented instruments and this lineup of emerging blockbuster drugs is remaking Eli Lilly because its older drugs, especially Prozac, are attacked by generic competitors. But this biotech symphony doesn't come cheap.

Lilly on Thursday reported sales growth of 17 percent in the fourth quarter and annual revenue growth of 14 percent, but disappointed investors with stagnant earnings. Despite strong sales, Lilly's profit grew only 1 percent in the fourth quarter of 2003 due to rising marketing, administrative research, and development costs. For the year, Lilly turned in a net income of $2.56 billion, a 5 percent decline compared to 2002.

Citing the conventional wisdom, many reports blame R&D expenses, which account for 20 percent of Lilly's sales, for the lower profits. But Lilly also disclosed rapidly rising marketing and administrative costs, which were up 23 percent in the quarter to $1.34 billion, for the ramp up for a number of new drugs. Marketing costs accounted for $400 million more in expenses during the fourth quarter than R&D.

Cymbalta, a new antidepressant Lilly will launch this summer, has been costly to develop. While the company hasn't disclosed the expenses for development of the drug, Cymbalta may have cost as much as $1 billion to bring within shooting distance of the market. Lilly, however, has already received $30 million of upfront payments that could total as much as $110 million from Quintiles Transnational, before the U.S. Food and Drug Administration approves it. Quintiles, which has 500 drug salespeople on the street, will take 8 percent of Cymbalta revenues for its services after the initial payments to Lilly.

In fact, the move to consumer advertising for drugs is driving most of the cost of new drugs. Soft-focus feel-good ads that tout drugs like Cialis, a new impotence pill, without explaining what Cialis does, are airing today to pave the way for consumer calls to their doctors demanding Cialis because it will make them more confident and happy. But investors might wonder, given the falling profits at Lilly, whether the consumer advertising strategy is paying off

source:-http://www.redherring.com

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