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News » Jan 2005

Pfizer profits up as pain hits rivals
January 20, 2005

PFIZER reported a fourfold increase in profits in the fourth quarter as it received an artificial boost from its painkillers Celebrex and Bextra after the rival Vioxx was withdrawn from the market.

Worldwide sales of Celebrex rose 24 per cent from the same period in 2003 to $1 billion (£530 million), while sales of Bextra surged 57 per cent to $417 million. These drugs are also now under the scrutiny of US regulators, along with the entire class of medicines known as Cox-2 inhibitors.

Merck, the rival drugmaker, withdrew Vioxx after a study showed that normal doses could double the risk of heart attack and stroke after 18 months. Last month, Pfizer said that one study of Celebrex showed similar safety issues.

The US Food and Drug Administration warned Pfizer last year that its advertisements made misleading statements about the safety and efficacy of Bextra and Celebrex.

Pfizer, the world’s largest drugs provider, said that net income for the period from October to December was $2.83 billion, or 38 cents a share, on revenues that rose 7 per cent to $14.92 billion. That compared with $602 million, or 8 cents a share, in the same period a year earlier, on revenues of $13.98 billion. The company said that generic competitors could diminish its sales, but gave no indication of its likely performance this year. Instead it indicated that it would provide a forecast in April.

Pfizer credited much of its success to sales of Lipitor, its blockbuster cholesterol medicine, sales of which rose 23 per cent in the quarter, to $3.3 billion. Sales of Viagra, its leading erectile dysfunction drug, advanced just 8 per cent in the period to $469 million, as competitors released rivals such as Eli Lilly’s Cialis and GlaxoSmithKline’s Levitra. Sales of Zoloft, its antidepressant, rose by a modest 7 per cent to $959 million.

Zoloft has suffered along with all selective serotonin reuptake inhibitors, the most commonly prescribed antidepressants, following fears regarding the use of such drugs in children.

Last month, Eli Lilly, which introduced Prozac in 1988, said that the market could remain dampened until 2007 because of side-effect concerns.

France’s drug regulator has requested more clinical information about AstraZeneca’s anticoagulant drug, Exanta, before considering licensing it for long-term use.
France is acting as the review nation for the product within the European Union. Exanta was rejected by US regulators last year because of concerns about potential liver damage.

source:-http://business.timesonline.co.uk

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