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Other Good Things About Viagra
June 19, 2006

As Chinese companies challenge the Viagra patent, research suggests ED drugs fight cardiovascular disease.

As a new study reported many positive side effects of erectile dysfunction drugs, a dozen Chinese drug companies announced Monday they will appeal a court decision to protect Pfizer’s Viagra patent in China.

Since Pfizer gained a Chinese patent for Viagra in 2001, it has received strong competition from Chinese companies such as Guangzhou Baiyunshan Medical Technology Development and Chongqing Kangerwei Pharmaceutical.

The appeal attempts to undo a decision taken earlier this month which re-validated Pfizer’s patent for the main ingredient in its little blue pill.

Meanwhile, new findings may encourage sales of erectile dysfunction drugs, increasing the stakes of the legal proceedings.

A review of medical research on the drugs conducted by scientists at Cedars-Sinai Medical Center in Los Angeles has found they produce mostly positive effects in the body other than those for which they were intended.

The three ED drugs on the market - Pfizer’s Viagra, GlaxoSmithKline’s Levitra, and Eli Lilly’s Cialis - all interfere with the action of an enzyme called phosphodiesterase-5. They seem to help in many medical conditions where relaxation of the smooth muscle around artery walls is desired.

“The original intention was to develop PDE-5 inhibitors as a treatment for angina, chest pain that occurs when the heart is starved for oxygen,” said Ernst R. Schwarz, a cardiologist at Cedars-Sinai Medical Center who specializes in therapies for men who suffer from erectile dysfunction as well as cardiovascular conditions.

“Their effects on the heart appear to be all beneficial… PDE-5 inhibitors (PDE-5i) actually improve blood flow even in areas where there is a blockage of an artery, thereby having a protective effect on the heart muscle,” he added.

The U.S. Food and Drug Administration recently approved a new version of Viagra to treat pulmonary hypertension, a condition where high blood pressures in the lungs lead to heart problems, often in young women.

ED drugs have been associated with negative side effects in the past. In particular, Viagra has been linked to an eye condition called NAION, or non-arteric anterior ischemic optic neuropathy (see Viagra-Blindness Link Probed). However, the review found no evidence to support the concerns.

“Even though individual cases have been reported for all PDE-5i, these recently published data do not suggest an increased incidence of [NAION] in men who took PDE-5i for ED,” it reads.

Source: http://www.redherring.com/article.aspx?a=17301

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